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Molecule Authority

 
Low density lipoprotein receptor-related protein 1
 
 
Cell surface receptor
Receptor activity
Cell communication ; Signal transduction

ALTERNATE NAMES   DISEASES   PTMs & SUBSTRATES  
SUMMARY SEQUENCE INTERACTIONS EXTERNAL LINKS  

 
  General            
 
Gene Symbol:LRP1 Molecular Weight (Da) :504605 Gene Map Locus:12q13-q14
 
 
 
  Localization           
 
Primary Endoplasmic reticulum  Alternate Plasma membrane  Golgi apparatus  Endosome  Extracellular  Nucleus 

 
   
 
  Domains and Motifs            
 
Domains Motifs
LDLA   26 - 66
LDLA   71 - 110
EGFL   112 - 149
EGFCA   150 - 189
LDLRB   272 - 314
LDLRB   315 - 358
LDLRB   359 - 401
EGFL   477 - 520
LDLRB   551 - 593
LDLRB   594 - 637
LDLRB   640 - 689
LDLRB   690 - 733
EGFL   806 - 843
LDLA   853 - 892
LDLA   894 - 933
LDLA   935 - 973
LDLA   975 - 1013
LDLA   1014 - 1053
LDLA   1061 - 1099
LDLA   1103 - 1142
LDLA   1144 - 1184
EGF   1185 - 1221
EGFL   1226 - 1262
LDLRB   1289 - 1331
LDLRB   1336 - 1378
LDLRB   1379 - 1423
LDLRB   1424 - 1468
LDLRB   1470 - 1512
EGFL   1539 - 1579
LDLRB   1605 - 1649
LDLRB   1650 - 1694
LDLRB   1697 - 1734
LDLRB   1735 - 1776
EGFL   1849 - 1887
LDLRB   1914 - 1956
LDLRB   1957 - 1999
LDLRB   2000 - 2043
LDLRB   2044 - 2086
LDLRB   2088 - 2130
EGF   2159 - 2194
LDLRB   2275 - 2317
LDLRB   2323 - 2368
LDLRB   2369 - 2411
LDLRB   2412 - 2453
EGFL   2481 - 2518
LDLA   2523 - 2563
LDLA   2565 - 2602
LDLA   2604 - 2641
LDLA   2659 - 2690
LDLA   2695 - 2732
LDLA   2733 - 2771
LDLA   2773 - 2814
LDLA   2815 - 2855
LDLA   2857 - 2899
LDLA   2903 - 2941
EGF   2944 - 2980
EGFCA   2982 - 3022
LDLRB   3049 - 3093
LDLRB   3094 - 3136
LDLRB   3137 - 3180
LDLRB   3181 - 3223
LDLRB   3224 - 3264
EGFL   3293 - 3331
LDLA   3333 - 3371
LDLA   3373 - 3410
LDLA   3412 - 3450
LDLA   3452 - 3491
LDLA   3493 - 3533
LDLA   3535 - 3572
LDLA   3574 - 3611
LDLA   3612 - 3649
LDLA   3653 - 3692
LDLA   3694 - 3733
LDLA   3740 - 3778
EGFL   3824 - 3861
LDLRB   3892 - 3934
LDLRB   3950 - 3992
LDLRB   3993 - 4036
LDLRB   4037 - 4079
EGFL   4150 - 4183
EGF   4200 - 4231
EGFL   4232 - 4268
EGFL   4271 - 4304
EGFL   4307 - 4340
EGFL   4343 - 4375
EGFL   4376 - 4409
TM   4420 - 4444
SP   1 - 19
 
  Expression           
 
Site of Expression
Astrocyte
Brain
Colon
Cytotrophoblast
Endometrium
Eye
Gastrointestinal Tract
Granulosa lutein cell
Kidney
Leydig cell
Liver
Lung
Lymphoid stem cell
Macrophage
Neuron
Placenta
Plasma
Retina
Skeletal muscle
Skin
Smooth muscle
Syncytiotrophoblast

  Human Proteinpedia   

Site of Expression
Normal Tissue
Blood plasma
Brain
Liver
Ovary
Saliva
Disease Tissue
 
Cell Line
HeLa

 
   
 
 
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