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Molecule Authority

 

FGF receptor 3
 
 
Receptor tyrosine kinase
Transmembrane receptor protein tyrosine kinase activity
Enzyme linked receptor protein signaling pathway ; Cellular morphogenesis during differentiation

Isoform 1

 
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  General            
 
Gene Symbol:FGFR3 Molecular Weight (Da) :87709 Gene Map Locus:4p16.3
 
 
 
  Localization           
 
Primary Plasma membrane  Alternate Nucleus  Cytoplasm  Cytoplasmic vesicle  Perinuclear vesicle 

 
   
 
  Domains and Motifs            
 
Domains Motifs
Ig_LIKE   52 - 126
IGC2   167 - 235
IGC2   266 - 346
TM   373 - 395
Tyr_Kinase   472 - 748
SP   1 - 23
 
  Expression           
 
Site of Expression
Bile duct
Brain
Cartilage
Cervix
Colon
Cornea
Corneal endothelial cell
Corneal epithelial cell
Coronary artery
Duodenum
Heart
Hepatocyte
Intestine
Islets of Langerhans
Kidney
Liver
Lymph node
Muscularis mucosa
Nervous system
Oviduct
Pancreas
Parathyroid
Pituitary acidophil
Pituitary basophil
Prostate
Respiratory system
Schwann cell
Skin
Sublingual gland
Submandibular gland
Submucosa
Sympathetic (chain) ganglionic trunk
Thymus
Thyroid gland
Uterus
Vermiform appendix

  Human Proteinpedia   

Site of Expression
Normal Tissue
Adrenal gland
Bone marrow
Brain
Cerebellum
Cerebral cortex
Colon
Epididymis
Hippocampus
Liver
Nasopharynx
Oesophagus
Oral mucosa
Parathyroid
Placenta
Rectum
Skin
Small intestine
Testis
Tonsil
Urinary bladder
Vagina
Vulva
Disease Tissue
Breast cancer
Cervical cancer
Colo-rectal cancer
Endometrial cancer
Head & neck cancer
Liver cancer
Lung cancer
Malignant carcinoid
Malignant glioma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Skin cancer
Testis cancer
Urothelial cancer
Cell Line
HeLa
K-562

 
   
 
 
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