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Molecule Authority

 
Megalin
 
 
Cell surface receptor
Receptor activity
Cell communication ; Signal transduction

ALTERNATE NAMES   DISEASES   PTMs & SUBSTRATES  
SUMMARY SEQUENCE INTERACTIONS EXTERNAL LINKS  

 
  General            
 
Gene Symbol:LRP2 Molecular Weight (Da) :521956 Gene Map Locus:2q24-q31
 
 
 
  Localization           
 
Primary Plasma membrane  Alternate  

 
   
 
  Domains and Motifs            
 
Domains Motifs
LDLA   27 - 64
LDLA   66 - 105
LDLA   107 - 144
LDLA   146 - 181
LDLA   182 - 219
LDLA   221 - 258
LDLA   265 - 303
EGFL   311 - 347
EGFL   348 - 386
LDLRB   415 - 458
LDLRB   459 - 501
LDLRB   502 - 548
LDLRB   549 - 591
LDLRB   593 - 635
EGFL   662 - 705
LDLRB   733 - 775
LDLRB   776 - 818
LDLRB   819 - 861
LDLRB   862 - 904
LDLRB   906 - 947
EGFL   973 - 1014
LDLA   1025 - 1062
LDLA   1066 - 1103
LDLA   1108 - 1145
LDLA   1148 - 1185
LDLA   1186 - 1224
LDLA   1229 - 1268
LDLA   1270 - 1307
LDLA   1311 - 1350
EGFCA   1390 - 1429
LDLRB   1459 - 1500
LDLRB   1501 - 1543
LDLRB   1544 - 1589
LDLRB   1590 - 1632
LDLRB   1634 - 1676
EGFL   1700 - 1741
LDLRB   1770 - 1811
LDLRB   1812 - 1855
LDLRB   1858 - 1910
LDLRB   1911 - 1953
LDLRB   1954 - 1993
EGFL   2018 - 2059
LDLRB   2087 - 2134
LDLRB   2135 - 2181
LDLRB   2182 - 2225
LDLRB   2226 - 2268
LDLRB   2290 - 2331
EGFL   2345 - 2383
LDLRB   2458 - 2500
LDLRB   2502 - 2542
LDLRB   2543 - 2585
LDLRB   2586 - 2626
EGFL   2654 - 2693
LDLA   2699 - 2738
LDLA   2740 - 2777
LDLA   2779 - 2819
LDLA   2821 - 2861
LDLA   2863 - 2901
LDLA   2905 - 2945
LDLA   2947 - 2990
LDLA   2992 - 3029
LDLA   3031 - 3070
LDLA   3074 - 3111
EGFCA   3152 - 3192
LDLRB   3219 - 3261
LDLRB   3262 - 3304
LDLRB   3310 - 3356
LDLRB   3357 - 3399
LDLRB   3400 - 3441
EGFL   3468 - 3509
LDLA   3511 - 3550
LDLA   3552 - 3591
LDLA   3593 - 3632
LDLA   3633 - 3673
LDLA   3677 - 3716
LDLA   3718 - 3756
LDLA   3758 - 3795
LDLA   3797 - 3834
LDLA   3841 - 3880
LDLA   3882 - 3922
LDLA   3927 - 3964
EGFCA   4007 - 4048
LDLRB   4134 - 4176
LDLRB   4177 - 4220
LDLRB   4221 - 4264
LDLRB   4265 - 4304
EGFL   4332 - 4368
EGFL   4381 - 4410
TM   4424 - 4446
SP   1 - 25
 
  Expression           
 
Site of Expression
Brain
Epididymis
Fetus
Kidney
Lung
Parathyroid
Placenta
Proximal convoluted tubule

  Human Proteinpedia   

Site of Expression
Normal Tissue
Liver
Disease Tissue
 
Cell Line
HeLa

 
   
 
 
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