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Molecule Authority

 
Low density lipoprotein receptor-related protein 6
 
 
Structural protein
Structural molecule activity
Cell growth and/or maintenance

ALTERNATE NAMES   DISEASES   PTMs & SUBSTRATES  
SUMMARY SEQUENCE INTERACTIONS EXTERNAL LINKS  

 
  General            
 
Gene Symbol:LRP6 Molecular Weight (Da) :180429 Gene Map Locus:12p11-p13
 
 
 
  Localization           
 
Primary Plasma membrane  Alternate  

 
   
 
  Domains and Motifs            
 
Domains Motifs
LDLRB   43 - 85
LDLRB   87 - 129
LDLRB   130 - 173
LDLRB   174 - 216
LDLRB   217 - 258
EGF   285 - 324
LDLRB   352 - 394
LDLRB   395 - 437
LDLRB   438 - 481
LDLRB   482 - 524
LDLRB   525 - 565
EGF   591 - 628
LDLRB   654 - 696
LDLRB   696 - 739
LDLRB   740 - 783
LDLRB   784 - 825
LDLRB   825 - 865
EGF   892 - 930
LDLRB   957 - 999
LDLRB   1001 - 1048
LDLRB   1049 - 1093
LDLRB   1094 - 1136
LDLRB   1137 - 1177
LDLA   1248 - 1287
LDLA   1288 - 1324
LDLA   1325 - 1362
TM   1371 - 1393
SP   1 - 25
 
  Expression           
 
Site of Expression
Brain
Heart
Kidney
Liver
Lung
Ovary
Pancreas
Placenta
Prostate
Skeletal muscle
Spleen
Testis

  Human Proteinpedia   

Site of Expression
Normal Tissue
Adrenal gland
Appendix
Bone marrow
Breast
Bronchus
Cerebellum
Cerebral cortex
Colon
Duodenum
Endometrium
Epididymis
Fallopian tube
Gall bladder
Hippocampus
Kidney
Lateral ventricle
Liver
Lung
Lymph node
Nasopharynx
Oesophagus
Oral mucosa
Pancreas
Parathyroid
Placenta
Prostate
Rectum
Salivary gland
Seminal vesicle
Serum
Small intestine
Smooth muscle
Spleen
Stomach
Testis
Thyroid
Tonsil
Urinary bladder
Uterine cervix
Vulva
Disease Tissue
Breast cancer
Cervical cancer
Colo-rectal cancer
Endometrial cancer
Head & neck cancer
Liver cancer
Lung cancer
Malignant carcinoid
Malignant glioma
Malignant lymphoma
Malignant melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer
Cell Line
HeLa

 
   
 
 
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