BRCA1
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Molecule Authority

 

BRCA1
 
 
Transcription regulatory protein
Transcription regulator activity
Regulation of gene expression, epigenetic

Isoform 1

 
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  General            
 
HPRD ID:00218 Molecular Weight (Da) :207721
Gene Symbol:BRCA1 Gene Map Locus:17q21
 
 
 
  Localization           
 
Primary Nucleus  Alternate Cytoplasm  Centrosome  Perinuclear region  Mitochondrion 

 
   
 
  Domains and Motifs            
 
Domains Motifs
BRCT   1644 - 1726
BRCT   1758 - 1845
RING   24 - 64
CC   1392 - 1424
NES   22 - 30
NLS   503 - 508
NLS   606 - 615
NES   81 - 99
 
  Expression           
 
Site of Expression
Brain
Cerebral cortex
Colon
Fetus
Heart
Kidney
Leukocyte
Liver
Lymph node
Lymphocyte
Mammary epithelium
Mammary gland
Oesophagus
Ovary
Pancreas
Prostate
Skeletal muscle
Small intestine
Spermatocyte
T Cell
Testis
Thyroid gland

  Human Proteinpedia   

Site of Expression
Normal Tissue
Blood plasma
CD8+ T Cells
Fetal Ovary
Fetal Testis
Disease Tissue
 
Cell Line
HeLa

 
   
  Isoform Specific            
 
  Localization           
 
Primary Nucleus  Alternate Cytoplasm  
 
 
 
 
 
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