Bruton`s tyrosine kinase
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Molecule Authority

 

Bruton`s tyrosine kinase
 
 
Tyrosine kinase
Protein-tyrosine kinase activity
Cell communication ; Signal transduction

     
 

 
  General            
 
HPRD ID:02248 Molecular Weight (Da) :76281
Gene Symbol:BTK Gene Map Locus:Xq21.33-q22
 
 
 
  Localization           
 
Primary Cytoplasm  Alternate Plasma membrane  Nucleus 

  Human Proteinpedia   

Localization
Cytoplasm  

 
   
 
  Domains and Motifs            
 
Domains Motifs
BTK   135 - 171
SH3   217 - 273
SH2   279 - 368
PH   4 - 135
Tyr_Kinase   402 - 651
 
  Expression           
 
Site of Expression
B Cell
Hematopoietic stem cell
Leukocyte
Plasma cell
Platelet
T Cell

  Human Proteinpedia   

Site of Expression
Normal Tissue
Adrenal gland
Adrenal
Appendix
B Cells
Bone marrow
Breast
Bronchus
CD8+ T Cells
Cerebral cortex
Colon
Duodenum
Endometrium
Epididymis
Fallopian tube
Fetal Liver
Fetal Ovary
Gall bladder
Gallbladder
Hippocampus
Immature Dendritic cell
Kidney
Lateral ventricle
Liver
Lung
Lymph node
Monocytes
NK Cells
Pancreas
Placenta
Platelet
Platelets
Prostate
Rectum
Retina
Salivary gland
Seminal vesicle
Skin
Spinal Cord
Spleen
Stomach
Testis
Tonsil
Urinary Bladder
Urinary bladder
Uterine cervix
Vagina
Vulva
Disease Tissue
Breast cancer
Cervical cancer
Colo-rectal cancer
Endometrial cancer
Head & neck cancer
Liver cancer
Lung cancer
Malignant carcinoid
Malignant glioma
Malignant lymphoma
Malignant melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer
Cell Line
HeLa
Jurkat
K-562
Ramos
U937 cells

 
   
 
 
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